funnily enough,one way to counteract poison is by use of another poison.
BarGamer
Chinese superstition, and will probably end up getting you killed, cuz, you know, you have two different poisons in you.
JWLM
Not quite true. For instance, one of the two antidotes to methanol is ethanol. Lots of ethanol. Violently ill, sick-making ethanol. (Yes, ethanol is a poison. We’re just able to break it down to less poisonous things. Mostly. It just takes a while.)
It’s a nasty treatment, but it’s better than going blind and then dying.
K^2
Ethanol is a somewhat questionable treatment for methanol poisoning. At least, in self-administered kind of way. The same mechanism, however, can also be used to prevent death from ethylene glycol (antifreeze) poisoning in a more reliable way. Ethylene glycol is converted to glycolic acid using the same enzyme that breaks down ethanol. Glycolic acid is then converted to oxalic acid, which precipitates in kidneys and causes them to fail. That’s what usually kills you. If you keep your liver busy with ethanol, it reduces rate of oxalic acid production, and most of antifreeze leaves your body via urine.
The process is similar for mehtanol. One of the reasons it’s poisonous is due to being converted to formic acid by the liver, again, using the same enzyme. Consuming lots of ethanol will help with that. However, both ethanol and methanol are CNS depressants. So taking too much ethanol together with ethanol will simply kill you due to alcohol poisoning, making it very iffy for self-medication. Then again, if your options are drinking loads of vodka or doing nothing, in both of these cases, you might as well take a chance with vodka.
JWLM
Yes, and there’s a better treatment, formipazole, which blocks the transformation into formaldehyde or formic acid. It’s got it’s own problems (it make ethanol a much more powerful intoxicant while mostly eliminating the hangover,) but it’s a better treatment if you can get it.
However, if you can’t, a bottle of vodka is as good a place to start as any.
tinfoil theory
There is a cure for hangovers?
And it makes ethanol more potent?
Clif
So naturally there is a drink which incorporates it?
tinfoil theory
I think you meant fomepizole.
ninja_jesus
Also, better to get your pet piss drunk than for their insides to liquefy.
There are actually some poisons for which the treatment — or at least a treatment — is another poison. For instance, Strychnine poisoning [i]can[/i] be treated with Curare.
I [b]think[/b] I remember hearing of some toxin whose immediate treatment was arsenic, on the principle that the arsenic would interfere with the action of the primary toxin, and could then itself be chelated out later.
That Damn Rat
Want an actual example of poison fighting poison? Take atropine, a derivative of Deadly nightshade can be used to counter the effects of organo-phosphate poisons, such Sarin nerve gas.
Jen Aside
just shove a bezoar down his throat
talantus
i can’t deny that. i only remember hearing it years ago…
but i do remember a documentary about a man who injected himself a little snake venom everyday and thus created a resistance to it. that could work too.
MerleBlue
That’s known as “Mithritadism”, after Mithradites VI, who followed the practice (and, after being captured by his enemies, tried to poison himself and failed. Whoops.)
It works for certain types of poison, but not all; there are some poisonous substances that accumulate in the tissues with increasingly bad effects, so trying that strategy will only make it worse.
Time Sage
Actually many anti-venoms are refined from posions.
Kelly
That is not remotely the same thing. Cause it has been refined so it isn’t a poison anymore…
Rodrigo
The difference between a poison and a medicine is the dose!
Gadgeteer Smashwidget
In fact, nearly *all* anti-venom is derived from the poisons they cure. Snake and spider venom, for example.
BH
When author Jack London killed himself, he took two different poisons, thinking that the two of them combined would kill him quickly and painlessly. Instead, they counteracted each other, and he lingered in agony for several days before he finally died painfully.
Ashirogi
Later biographers have contested that. The World of Jack London website discusses the issue.
I happen to really like water, thank you very much. Give your water to me, if you don’t want it.
The Gorram Batguy
As your comment has been distanced, by many lines of other comments, from the comment to which it was a response, I read it as if it was without context.
As such, my brain applied context, and I read it in the Dune sense of taking “somebody’s water”. That made it much more interesting.
As you were.
Whoa, a Hanamonogatari viewer has been spotted or are you a LN reader? 🙂
Saru
elaborate.
Just for kix
I was replying to the “Average Loser”, his quote “If you can’t be the antidote, become the poison. Otherwise you’re just lukewarm water helpful to none.” is a quote from an anime series called Hanamonogatari (which is an adaptation of a light novel (LN) of the same name).
Possible. Oh, I hope so. I really want this to go well for them.
Not because porn. Because I really, really like this ship.
… not that porn hurts or anything.
Lemme check, lessee, rent…landlords…apartments…Ooh! There’s a game where you are the devil and run an apartment building for various monsters! And it’s only $3.99!
Gigafreak
I thought that game was WiiWare rather than Steam.
255 thoughts on “Supposed”
An Average Loser
Tension.
Hannah
Makes the heart grow fonder.
Kahhhhhhhle
I thought that was absinthe. Or was it absence? I always mix those two up.
Cheryl
That gurl is poooossiiioooon POSION dodododododo
gordon blvd
……….NEVER trust a big butt and a smile…………
Deanatay
Miss her, kiss her, love her (wrong move, yer dead)
Rachel Roth
Okay. . . but why would that matter? No one eats dodo!
LittleMountain
At the risk of repeating my comment from the Danny/Ethan strip a few days ago:
JUST MAKE OUT ALREADY
Jen Aside
“LET’S BE POISON TOGETHER AND POISON THE WORLD”
An Average Loser
If you can’t be the antidote, become the poison. Otherwise you’re just lukewarm water helpful to none.
talantus
funnily enough,one way to counteract poison is by use of another poison.
BarGamer
Chinese superstition, and will probably end up getting you killed, cuz, you know, you have two different poisons in you.
JWLM
Not quite true. For instance, one of the two antidotes to methanol is ethanol. Lots of ethanol. Violently ill, sick-making ethanol. (Yes, ethanol is a poison. We’re just able to break it down to less poisonous things. Mostly. It just takes a while.)
It’s a nasty treatment, but it’s better than going blind and then dying.
K^2
Ethanol is a somewhat questionable treatment for methanol poisoning. At least, in self-administered kind of way. The same mechanism, however, can also be used to prevent death from ethylene glycol (antifreeze) poisoning in a more reliable way. Ethylene glycol is converted to glycolic acid using the same enzyme that breaks down ethanol. Glycolic acid is then converted to oxalic acid, which precipitates in kidneys and causes them to fail. That’s what usually kills you. If you keep your liver busy with ethanol, it reduces rate of oxalic acid production, and most of antifreeze leaves your body via urine.
The process is similar for mehtanol. One of the reasons it’s poisonous is due to being converted to formic acid by the liver, again, using the same enzyme. Consuming lots of ethanol will help with that. However, both ethanol and methanol are CNS depressants. So taking too much ethanol together with ethanol will simply kill you due to alcohol poisoning, making it very iffy for self-medication. Then again, if your options are drinking loads of vodka or doing nothing, in both of these cases, you might as well take a chance with vodka.
JWLM
Yes, and there’s a better treatment, formipazole, which blocks the transformation into formaldehyde or formic acid. It’s got it’s own problems (it make ethanol a much more powerful intoxicant while mostly eliminating the hangover,) but it’s a better treatment if you can get it.
However, if you can’t, a bottle of vodka is as good a place to start as any.
tinfoil theory
There is a cure for hangovers?
And it makes ethanol more potent?
Clif
So naturally there is a drink which incorporates it?
tinfoil theory
I think you meant fomepizole.
ninja_jesus
Also, better to get your pet piss drunk than for their insides to liquefy.
Ray Radlein
There are actually some poisons for which the treatment — or at least a treatment — is another poison. For instance, Strychnine poisoning [i]can[/i] be treated with Curare.
I [b]think[/b] I remember hearing of some toxin whose immediate treatment was arsenic, on the principle that the arsenic would interfere with the action of the primary toxin, and could then itself be chelated out later.
That Damn Rat
Want an actual example of poison fighting poison? Take atropine, a derivative of Deadly nightshade can be used to counter the effects of organo-phosphate poisons, such Sarin nerve gas.
Jen Aside
just shove a bezoar down his throat
talantus
i can’t deny that. i only remember hearing it years ago…
but i do remember a documentary about a man who injected himself a little snake venom everyday and thus created a resistance to it. that could work too.
MerleBlue
That’s known as “Mithritadism”, after Mithradites VI, who followed the practice (and, after being captured by his enemies, tried to poison himself and failed. Whoops.)
It works for certain types of poison, but not all; there are some poisonous substances that accumulate in the tissues with increasingly bad effects, so trying that strategy will only make it worse.
Time Sage
Actually many anti-venoms are refined from posions.
Kelly
That is not remotely the same thing. Cause it has been refined so it isn’t a poison anymore…
Rodrigo
The difference between a poison and a medicine is the dose!
Gadgeteer Smashwidget
In fact, nearly *all* anti-venom is derived from the poisons they cure. Snake and spider venom, for example.
BH
When author Jack London killed himself, he took two different poisons, thinking that the two of them combined would kill him quickly and painlessly. Instead, they counteracted each other, and he lingered in agony for several days before he finally died painfully.
Ashirogi
Later biographers have contested that. The World of Jack London website discusses the issue.
Now back to your regularly scheduled dongs.
Saru
I happen to really like water, thank you very much. Give your water to me, if you don’t want it.
The Gorram Batguy
As your comment has been distanced, by many lines of other comments, from the comment to which it was a response, I read it as if it was without context.
As such, my brain applied context, and I read it in the Dune sense of taking “somebody’s water”. That made it much more interesting.
As you were.
Just for kix
Whoa, a Hanamonogatari viewer has been spotted or are you a LN reader? 🙂
Saru
elaborate.
Just for kix
I was replying to the “Average Loser”, his quote “If you can’t be the antidote, become the poison. Otherwise you’re just lukewarm water helpful to none.” is a quote from an anime series called Hanamonogatari (which is an adaptation of a light novel (LN) of the same name).
Vree
I scrolled down just to see retorts to that line, I was not disappointed
Pink Freud
Damn you, you beat me to the punch and with almost exatly the same words! Well played.
Yotomoe
Billy and Ruth Become Harley and Ivy.
MissQuinn
If somebody does not draw this I can personally promise an internet revolt!
Yotomoe
I could always draw it…
for a fee.
K^2
You take PayPal?
Yotomoe
I does. I does.
Plasma Mongoose
So who is the Joker then?
Jake
Howard.
Beachfox
Sal is The Joker. Dorothy is Lana Lang, and we all know who Amazigirl is.
DEADGAYROBOTS
Yeah. Carla
Clif
Sal’s secret identity?
Opus the Poet
Danny, who else?
Cybersnark
Yeah, actually. Billie threw herself at Danny, but he wasn’t interested.
That’s the Harley/Joker relationship in a nutshell.
DanMan9820
That’s not quite true. Danny was interested, he just didn’t want to bang her at the risk of losing any chance with Amber.
And I personally think it was one of Willis’s Walkyverse ship teases, like the Joyce/Walky one and the Mike/Amber one.
LiaHansen
ooooohhhhh, THEY’RE the slipshine.
Jen Aside
EVERYONE will be the Slipshine.
All in good time.
LeslieBean4Shizzle
Possible. Oh, I hope so. I really want this to go well for them.
Not because porn. Because I really, really like this ship.
… not that porn hurts or anything.
Yotomoe
No, Lia. The slipshine was inside of you all along.
Mrak
Or maybe the shipsline?
Doom Shepherd
AND THEN JOHN WAS A SLIPSHINE.
Kernanator
I just want to slam the skulls of these two idiots together and scream at them.
Jen Aside
But then how will they bang if you bang their heads in??
Disloyal Subject
Messily.
Opus the Poet
Uncoordinatedly, I think.
That Damn Rat
Maybe we could try banging their pelvises’ together instead?
Yotomoe
That sounds like something an insane person would do!
Doctor_Who
So alcohol is like games on Steam to Ruth. She’ll compulsively buy them, but never get around to actually using them.
…That being the case, I may need to look into some sort of Steamaholics Anonymous.
An Average Loser
C-Can you give the hotline number please? It’s getting to the point that I can’t pay rent. . .
Doctor_Who
Lemme check, lessee, rent…landlords…apartments…Ooh! There’s a game where you are the devil and run an apartment building for various monsters! And it’s only $3.99!
Gigafreak
I thought that game was WiiWare rather than Steam.
timemonkey
Just pretend rent is a new game that comes out each month.
masterofbones
I’m not paying $500 on a game.
Deanatay
ONLY one game?? On STEAM??? Bwhahahahahahhaaaa!
Jen Aside
One of my favourite games on Steam is trying to get more games without actually giving Steam any more money.
Almost lost that game, but somehow my friends/family keep getting me more… [also, Steam summer sale voting]
David Alexander McDonald
I have a sneaking suspicion that HumbleBundle is like crack for some ppeople. THERE IS SHOVELWARE. I MUST HAVE IT.
Israfel
I blame the sales. I always get games for someday when they are on sale.
Salmo